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​DHEA counteracts AGE(Advanced Glycation End product) formation

By Dr. Richard K Bernstein 2 years ago 950 Views No comments

This is an article published in Diabetes Care a number of years ago, but it's still pertinent. I stumbled upon it when I go through my reminders of important facts.

Many people have asked me on these tele-seminars over the years, how do we stop glycation of proteins in the body? That assumes that you're going to have elevated blood sugars. We know that most of the complications of diabetes are caused by the attachment of glucose to important proteins throughout the body.

We've gone into detail about some of these things in the past, and if we could stop this from happening, we could prevent many of the complications of diabetes. Well, the best way to stop this from happening is to have normal blood sugars, and as those of you who are using my book, Diabetes Solution know, that's not too hard to do.

But you have to control your overeating if you eat too much carbohydrate, and you have to stop following the ADA Guidelines that recommend high carbohydrate. So number one is, normalize blood sugars. For those people who can't possibly control their overeating, DHEA, which is dehydroepiandrosterone and is a precursor to testosterone and estrogen, is something that apparently inhibits glycosolation of proteins.

For those of you who want to go to the original source, the article is entitled "Dehydroepiandrosterone Administration Counteracts Oxidative Imbalance and Advanced Glycation End Product Formation in Type 2 Diabetic Patients" This is from Diabetes Care Volume 30, 2007. You can access the PDF here.

Now, DHEA you can purchase at most health food stores. I can't testify about the quality of all different sources of DHEA. You have to use a reliable manufacturer, and you don't want to overdose yourself. So I would think that, depending upon your size, and certainly not for children, we would probably take 25 or 50 mg per day. But this is speculation based upon one article in one major journal, so that's about the information that I can give you. Shop for DHEA

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